D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-methyl- (9CI) - Names and Identifiers
Name | D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-methyl- (9CI)
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Synonyms | BOC-O-METHYL-D-SERINE N-Boc-(D)-O-Methylserine BOC-R-serine methyl ether (R)-N-Boc-2-aMino-3-Methoxypropionic acid O-methyl-N-(phenylmethyl)-D-Serine methyl ester 2-(tert-butoxycarbonylamino)-3-methoxypropanoic acid O-Methyl-N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-serine D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-methyl- (9CI) (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-methoxypropanoic acid
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CAS | 86123-95-7
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EINECS | 1308068-626-2 |
InChI | InChI=1/C9H17NO5/c1-9(2,3)15-8(13)10-6(5-14-4)7(11)12/h6H,5H2,1-4H3,(H,10,13)(H,11,12)/t6-/m1/s1 |
D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-methyl- (9CI) - Physico-chemical Properties
Molecular Formula | C9H17NO5
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Molar Mass | 219.24 |
Density | 1.148±0.06 g/cm3(Predicted) |
Boling Point | 355.8±37.0 °C(Predicted) |
pKa | 3.52±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.46 |
D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-methyl- (9CI) - Introduction
D-Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-methyl- (9CI) is an organic compound with the chemical formula C9H17NO5. It is an esterified derivative of methylated D-serine, and its chemical name is N-[(1,1-dimethylethoxy) carbonyl]-O-methyl-D-serine.
D-Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-methyl- (9CI) is mainly used as a reagent for biochemical research and organic synthesis. As a protecting group, it can be used in the synthesis of other amide compounds, especially during peptide synthesis, to protect the hydroxyl group of serine. D-Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-methyl- (9CI) is also used in the synthesis of biologically active compounds, such as drugs, pharmaceutical intermediates, etc.
D-Serine, the preparation method of N-[(1,1-dimenthylethoxy) carbonyl]-O-methyl- (9CI) is to react D-serine and Boc-2-oxo -2-methyl acetic anhydride under alkaline conditions to produce the target product D-Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-methyl- (9CI). After completion of the reaction, the product is purified by crystallization or column chromatography or the like.
Regarding safety information, D-Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-methyl- (9CI) is a chemical substance that needs to be properly handled and stored in the laboratory. It may be irritating to the eyes and skin, so it is necessary to wear appropriate protective equipment, such as laboratory gloves, safety glasses, etc. In addition, the compound should not be directly inhaled or ingested and should be kept away from children and pets. In the event of an accident, you should immediately seek help from professionals to deal with it. When stored, it should be kept in a dry, cool place, away from fire and oxidizing agents.
Last Update:2024-04-09 20:52:54